Development of Ultraviolet Spectrophotometric Method for Analysis of Lornoxicam in Solid Dosage Forms

Application of hydrotropic solubilization in spectrophotometric analysis of Esomeprazole and Itopride pharmaceutical combined tablet dosage forms

Two simple, accurate and precise methods for simultaneous estimation of Esomeprazole and Itopride in bulk drug and tablet dosage form have been described. Method-A employs formation and solving of simultaneous equation using 231 and 370 nm as two analytical wavelengths. Method -B is Absorption ratio method, which uses 308 and 331 nm as two analytical wavelengths.Beer’s law was obeyed in the con...

Spectrophotometric Analysis of Vardenafil in Tablet Dosage Forms by Using Electrophilic Coupling Reagents

Two new spectrophotometric methods (M1 and M2) are developed for the determination of vardenafil in bulk and in tablet dosage forms. The method M1 involves oxidative coupling of vardenafil with 3-methyl-2-benzothiazolinone hydrazone hydrochloride in presence of ferric chloride in acidic medium yielding green colored chromogen with absorption maxima at 625 nm. The method M2 is based on the oxida...

Development and Validation of UV Spectrophotometric Method for Determination of Cefuroxime in Pharmaceutical Dosage forms

A rapid and sensitive UV-Visible spectroscopic method was developed for the estimation of cefuroxime in pure and its Pharmaceutical formulations. The method was based on the measurement of absorbance of Cefuroxime active moiety of Cefuroxime tablet at 277 nm using methanol as solvent. The absorbance was found to increase linearly with increase in concentration of Cefuroxime which was corroborat...

Spectrophotometric Methods for Determination of Sunitinib in Pharmaceutical Dosage Forms Based on Ion-pair Complex Formation

Three rapid spectrophotometric methods were developed for the determination of sunitinib based on the formation of ion-pair complex in acidic medium with bromocresol purple, bromothymol blue, and bromophenol blue. The formed ion-pair complexes, extractable with chloroform, were measured at 422 nm for bromocresol purple, 425 nm for bromothymol blue and 427 nm for bromophenol blue. All these meth...

development of a dye-complex based spectrophotometric method for determination of azithromycin in bulk and dosage forms using alizarin red